Target
GlcB
Ligand
BDBM225393
Substrate
n/a
Meas. Tech.
DNTB-Coupled_Enzyme_Assay
IC50
>100000±n/a nM
Citation
 D3R, DD Sacchettini GlcB D3R 223:0 (2015) [PubMed]
Target
Name:
GlcB
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
80350.85
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
741
Sequence:
MTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQNQALLNARDELQAQIDKWHRRRVIEPIDMDAYRQFLTEIGYLLPEPDDFTITTSGVDAEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVIPETDGAEKGPTYNKVRGDKVIAYARKFLDDSVPLSSGSFGDATGFTVQDGQLVVALPDKSTGLANPGQFAGYTGAAESPTSVLLINHGLHIEILIDPESQVGTTDRAGVKDVILESAITTIMDFEDSVAAVDAADKVLGYRNWLGLNKGDLAAAVDKDGTAFLRVLNRDRNYTAPGGGQFTLPGRSLMFVRNVGHLMTNDAIVDTDGSEVFEGIMDALFTGLIAIHGLKASDVNGPLINSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQNTMKIGIMDEERRTTVNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMVRKGTMKSQPWILAYEDHNVDAGLAAGFSGRAQVGKGMWTMTELMADMVETKIAQPRAGASTAWVPSPTAATLHALHYHQVDVAAVQQGLAGKRRATIEQLLTIPLAKELAWAPDEIREEVDNNCQSILGYVVRWVDQGVGASKVPDIHDVALMEDRATLRISSQLLANWLRHGVITSADVRASLERMAPLVDRQNAGDVAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKARAAEKPAPSDRAGDDAAR
  
Inhibitor
Name:
BDBM225393
Synonyms:
Sacchettini_20
Type:
Small Organic Molecule
Emp. Form.:
C13H14O4
Mol. Mass.:
234.2479
SMILES:
CC(C)c1ccccc1C(=O)\C=C(/O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: