Target
SYK Kinase
Ligand
BDBM225562
Substrate
n/a
Meas. Tech.
SYK assay_HTRF
IC50
1.3±n/a nM
Citation
 D3R, DD GSK SYK Kinase D3R 225:0 (2015) [PubMed]
Target
Name:
SYK Kinase
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
32610.83
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
281
Sequence:
PEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
  
Inhibitor
Name:
BDBM225562
Synonyms:
GTC000266A | GTC000266B | GTC000266C
Type:
Small Organic Molecule
Emp. Form.:
C22H21FN8O
Mol. Mass.:
432.4535
SMILES:
Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Structure:
Search PDB for entries with ligand similarity: