Reaction Details Report a problem with these data
Target
Urokinase-type plasminogen activator
Ligand
BDBM237189
Substrate
n/a
Meas. Tech.
Enzyme Assay
pH
8.0000±n/a
IC50
50000±n/a nM
Comments
extracted
Citation
 Viskupicova, J; Danihelova, M; Majekova, M; Liptaj, T; Sturdik, E Polyphenol fatty acid esters as serine protease inhibitors: a quantum-chemical QSAR analysis. J Enzyme Inhib Med Chem 27:800-9 (2012) [PubMed]  Article 
Target
Name:
Urokinase-type plasminogen activator
Synonyms:
Urokinase-type plasminogen activator short chain A | U-plasminogen activator | UROK_HUMAN | Urokinase-type plasminogen activator/surface receptor | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator long chain A | 3.4.21.73 | Urokinase-type plasminogen activator chain B | PLAU | uPA
Type:
Enzyme
Mol. Mass.:
48528.62
Organism:
Human
Description:
P00749
Residue:
431
Sequence:
MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
  
Inhibitor
Name:
BDBM237189
Synonyms:
Rutin laurate
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCCCCCCCCCCC(=O)OC1C(C)OC(OCC2OC(Oc3c(oc4cc(O)cc(O)c4c3=O)-c3ccc(O)c(O)c3)C(O)C(O)C2O)C(O)C1O
Structure:
Search PDB for entries with ligand similarity: