Reaction Details Report a problem with these data
Target
Carbonic anhydrase 4
Ligand
BDBM237337
Substrate
n/a
Meas. Tech.
Carbonic Anhydrase I, II, IV and XII Assay
pH
7.5000±n/a
Temperature
298.1500±n/a K
IC50
498.8±0.0 nM
Comments
extracted
Citation
 Supuran, CT; Maresca, A; Gregán, F; Remko, M Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII. J Enzyme Inhib Med Chem 28:289-93 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) | CA-IV | Carbonate dehydratase IV | CAH4_HUMAN | CA4 | Carbonic anhydrase
Type:
Enzyme
Mol. Mass.:
35037.98
Organism:
Human
Description:
P22748
Residue:
312
Sequence:
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLR
  
Inhibitor
Name:
BDBM237337
Synonyms:
N-(3-morpholinopropyl)benzene-1,4-disulfonamide (I-2)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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