Reaction Details Report a problem with these data
Target
Carbonic anhydrase 13
Ligand
BDBM246554
Substrate
n/a
Meas. Tech.
Thermal Shift Assay (TSA)
pH
7.0000±n/a
Kd
286±n/a nM
Comments
extracted
Citation
 Zubriene, A; Capkauskaite, E; Gylyte, J; KiĊĦonaite, M; Tumkevicius, S; Matulis, D Benzenesulfonamides with benzimidazole moieties as inhibitors of carbonic anhydrases I, II, VII, XII and XIII. J Enzyme Inhib Med Chem 29:124-31 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
Carbonic anhydrase XIII (CA XIII) | CAH13_HUMAN | CA13 | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII)
Type:
Enzyme
Mol. Mass.:
29445.78
Organism:
Human
Description:
Q8N1Q1
Residue:
262
Sequence:
MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH
  
Inhibitor
Name:
BDBM246554
Synonyms:
4-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]benzenesulfonamide (1d)
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
NS(=O)(=O)c1ccc(cc1)C(=O)Cn1c(Cc2ccccc2)nc2ccccc12
Structure:
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