Reaction Details
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Baculoviral IAP repeat-containing protein 2 [174-256]
Ligand
BDBM298390
Substrate
n/a
Meas. Tech.
Enzyme Inhibition
IC50
23.0±n/a nM
Citation
Baker, TM; Fyfe, MC; Jones, G; Thom, SM Kinase inhibitors US Patent US10392346 Publication Date 8/27/2019 More Info.:
Target
Name:
Baculoviral IAP repeat-containing protein 2 [174-256]
Synonyms:
CIAP Bir2 | BIRC2_HUMAN | BIRC2 | API1 | MIHB | RNF48
Type:
Enzyme Catalytic Domain
Mol. Mass.:
9527.07
Organism:
Human
Description:
Q13490[174-256]
Residue:
83
Sequence:
TNPYSYAMSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSLET
Inhibitor
Name:
BDBM298390
Synonyms:
US10125100, Example 12 | 1-[5-tert-Butyl-3-(methanesulfonamido)-2-methoxy-phenyl]-3-[4-[[2-[3-methoxy-4-[2-[2-(2-methoxyethoxy)ethoxy]ethylsulfonyl]anilino]-4-pyridyl]oxy]-1-naphthyl]urea | US9751837, Example 12 | US10392346, Example 12 | US10941115, Example 12
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
