Reaction Details Report a problem with these data
Target
Interleukin-1 beta
Ligand
BDBM398042
Substrate
n/a
Meas. Tech.
IL-1beta Release Assay
IC50
>1000±n/a nM
Citation
 Karra, SR Indole derivatives and their use in neurodegenerative diseases US Patent  US10676433 Publication Date 6/9/2020 
Target
Name:
Interleukin-1 beta
Synonyms:
hIL-1beta | Interleukin 1-beta | Interleukin-1 beta | IL1B_HUMAN | IL1B | IL1F2
Type:
Cytokine
Mol. Mass.:
30734.47
Organism:
Human
Description:
P01584
Residue:
269
Sequence:
MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQLRISDHHYSKGFRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEPIFFDTWDNEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS
  
Inhibitor
Name:
BDBM398042
Synonyms:
US10322143, Compound 1 | US10323000, Compound 1 | US10676433, Compound 1
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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