PMID

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Article Title

Organization

1-Heteroarylpropan-2-ones as inhibitors of fatty acid amide hydrolase: Studies on structure-activity relationships and metabolic stability.

University Of M£Nster

Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain.

University Of Siena

Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors.

University Of Eastern Finland

Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).

University Of Eastern Finland

Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH).

Universit£

Synthesis and biological evaluation of open-chain analogs of cyclic peptides as inhibitors of cellular Shp2 activity.

Hebei University Of Science & Technology

Loratadine analogues as MAGL inhibitors.

University Of Eastern Finland

Novel tail and head group prostamide probes.

Northeastern University

Docking based virtual screening and molecular dynamics study to identify potential monoacylglycerol lipase inhibitors.

Jamia Hamdard (Hamdard University)

Identification and characterization of a new reversible MAGL inhibitor.

University Of Pisa

Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors.

University Of Eastern Finland

Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring.

Sapienza University Of Rome

(4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).

University Of M£Nster

An unprecedented reversible mode of action ofß-lactams for the inhibition of human fatty acid amide hydrolase (hFAAH).

Universit£

Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors.

Universite Catholique De Louvain

Sulfonyl fluoride inhibitors of fatty acid amide hydrolase.

Northeastern University

Assay and inhibition of diacylglycerol lipase activity.

Northeastern University

Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold.

Sapienza University Of Rome

Synthesis and pharmacological evaluation of 2,4-dinitroaryldithiocarbamate derivatives as novel monoacylglycerol lipase inhibitors.

Universit£

Structure-activity relationship of a new series of reversible dual monoacylglycerol lipase/fatty acid amide hydrolase inhibitors.

Universidad Complutense De Madrid

The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications.

Universit£

Fatty acid amide hydrolase inhibitors. 3: tetra-substituted azetidine ureas with in vivo activity.

Vernalis (R&D)

Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone.

Universit£

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects.

The Scripps Research Institute

Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors.

University Of Cagliari

Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors.

Louvain Drug Research Institute

beta-Lactams derived from a carbapenem chiron are selective inhibitors of human fatty acid amide hydrolase versus human monoacylglycerol lipase.

Universite Catholique De Louvain

The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors.

University Of Kuopio

3-Alkenyl-2-azetidinones as fatty acid amide hydrolase inhibitors.

Université

Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives.

University Of Pisa

Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications.

Liberty University

Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones.

Indian Institute Of Technology (Banaras Hindu University)

Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging.

Eth Zurich

Therapeutic Potential of Monoacylglycerol Lipase (MGL) Inhibitors as Treatment for Pain, Depression, Cancers, and Eye Conditions.

Therachem Research Medilab

Novel Aminocyclobutanes as Monoacylglycerol Lipase Modulators.

Smith, Gambrell & Russell

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Eth Z�Rich

Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold.

University Of Pisa

Heterocyclic Compounds as Monoacylglycerol Lipase (MAGL) Inhibitors.

Smith, Gambrell & Russell

Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening.

Nanchang University

Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2

Takeda Pharmaceutical

Hit to lead optimization of a series of N-[4-(1,3-benzothiazol-2-yl)phenyl]acetamides as monoacylglycerol lipase inhibitors with potential anticancer activity.

Hamdard University

Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.

University Of Pisa

The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis.

University Of Pisa

Novel Oxazine Monoacylglycerol Lipase (MAGL) Inhibitors.

Smith, Gambrell & Russell

Structural Optimization of 4-Chlorobenzoylpiperidine Derivatives for the Development of Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

University Of Pisa

Acylated 1

University Of M£Nster

The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL).

Janssen Research & Development

The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors.

Janssen Research & Development

Discovery of Aryl Formyl Piperidine Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase Inhibitors.

China Pharmaceutical University

Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors.

Northeastern University

Plant-Based Modulators of Endocannabinoid Signaling.

Concordia University Wisconsin

Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor.

University Of Pisa

Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment.

Mak Scientific

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.

Universit£

Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology.

Northeastern University

Multi-target-directed-ligands acting as enzyme inhibitors and receptor ligands.

Julius Maximilian University Of W£Rzburg

Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders.

Abide Therapeutics

Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors.

University Of Pisa

Design, synthesis, molecular modelling and in vitro cytotoxicity analysis of novel carbamate derivatives as inhibitors of Monoacylglycerol lipase.

Universit£

Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors.

Takeda Pharmaceutical

Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor.

University Of Pisa

Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors.

Universit£

Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system.

University Of Bern

Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation.

Pfizer

Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

University Of Ferrara

Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.

Pfizer

Discovery of Boronic Acids as Novel and Potent Inhibitors of Fatty Acid Amide Hydrolase.

University Of Oxford