Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 4627 of affinity data for UniProtKB/TrEMBL: P00797
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025935(CHEMBL3144404 | {1-[1-(1-{2-[1-(Benzylamino-methyl...)
Affinity DataKi:  0.0260nMAssay Description:Compound was tested for inhibition of hog kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50368278(CHEMBL1790497)
Affinity DataKi:  0.0400nMAssay Description:In vitro inhibition constants using recombinant human renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023090(Boc-Phe-His-Sta-Leu-4-amido-1-benzylpiperidine | C...)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50368274(CHEMBL1790492)
Affinity DataKi:  0.0430nMAssay Description:In vitro inhibition constants using recombinant human renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50012322(CHEMBL264524 | N-(2-Hydroxy-1,1-bis-hydroxymethyl-...)
Affinity DataKi:  0.0510nMAssay Description:In vitro inhibition of human renin by radio-immuno assay of angiotensin I (ANG I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023090(Boc-Phe-His-Sta-Leu-4-amido-1-benzylpiperidine | C...)
Affinity DataKi:  0.0640nMAssay Description:Inhibition of purified human kidney renin, fluorometric assay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025934(CHEMBL3144405 | {1-[1-(1-{2-[1-(1-Benzyl-piperidin...)
Affinity DataKi:  0.0640nMAssay Description:Compound was tested for inhibition of human kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023094(Boc-Phe-His-Sta-Leu-erythro-1,2-diphenyl-2-hydroxy...)
Affinity DataKi:  0.120nMAssay Description:Inhibition of hog kidney renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.160nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.190nMAssay Description:The compound was tested for inhibition of rhesus monkey plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023094(Boc-Phe-His-Sta-Leu-erythro-1,2-diphenyl-2-hydroxy...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023094(Boc-Phe-His-Sta-Leu-erythro-1,2-diphenyl-2-hydroxy...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025937(CHEMBL3144417 | {1-[1-{3-[1-(1-Carbamoyl-2-phenyl-...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.540nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50065428(CHEMBL3401350)
Affinity DataKi:  0.600nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM17941((2S,4S,5S)-5-[(2S)-2-[(2S)-2-benzyl-3-[(2-methylpr...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against aspartic protease renin.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50077669((S)-2-Benzyl-N-[(S)-1-((1S,2R,3S)-1-cyclohexylmeth...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against aspartic protease renin.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025945(CHEMBL3144416 | {1-[1-{3-[1-(1-Carbamoyl-2-phenyl-...)
Affinity DataKi:  0.880nMAssay Description:Inhibition of human kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50027362(1-[2-(Hydroxy-phenoxy-phosphorylamino)-propionyl]-...)
Affinity DataKi:  1nMAssay Description:Antihypertensive activity against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025941(CHEMBL3144415 | {1-[1-{3-[1-(1-Carbamoyl-2-phenyl-...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021129(1-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-p...)
Affinity DataKi:  1.20nMAssay Description:Antihypertensive activity against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023091(CHEMBL269752 | Iva-His-Pro-Phe-His-Sta-Leu-Phe-NH2)
Affinity DataKi:  1.5nMAssay Description:Inhibition of purified human kidney renin, fluorometric assay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataKi:  1.70nMAssay Description:Antihypertensive activity against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50065395(CHEMBL3401345)
Affinity DataKi:  2nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281638((2S,4S,5S)-6-Cyclohexyl-4-hydroxy-5-{(S)-3-(1H-imi...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to reninMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to reninMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50065426(CHEMBL3401348)
Affinity DataKi:  2.20nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025932(CHEMBL3144406 | Nitrate salt of {1-[1-(1-{2-[1-(1-...)
Affinity DataKi:  3.60nMAssay Description:Compound was tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  3.70nMAssay Description:Binding affinity of the compound was determined against Nicotinic acetylcholine receptor using [3H]-(-)-nicotine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023050(CHEMBL40928 | {1-[1-(1-{2-[1-(1-Carbamoyl-2-phenyl...)
Affinity DataKi:  4.80nMAssay Description:Compound was tested for inhibition of human kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50065424(CHEMBL3401346)
Affinity DataKi:  6nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023096(Boc-Phe-His-Sta-Leu-(+)-alpha-phenylthylamide | CH...)
Affinity DataKi:  6nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405191(CHEMBL269752)
Affinity DataKi:  6.20nMAssay Description:The compound was tested for inhibition of rabbit plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023054(CHEMBL291091 | {1-[1-(1-{2-[1-(1-Carbamoyl-2-pheny...)
Affinity DataKi:  7nMAssay Description:Compound was evaluated for inhibitory activity against human kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  7nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025946(4-[2-(2-Acetylamino-3-phenyl-propionylamino)-3-(1H...)
Affinity DataKi:  7.70nMAssay Description:Inhibition of human kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022507(CHEMBL3349407 | H2N-His-Pro-Phe-His-Sta-Leu-PheOMe)
Affinity DataKi:  8nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405191(CHEMBL269752)
Affinity DataKi:  8.80nMAssay Description:Inhibition of human kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022520(CHEMBL3349395 | H2N-Abu-Pro-Phe-Abu-Sta-Leu-PheOMe)
Affinity DataKi:  9nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405191(CHEMBL269752)
Affinity DataKi:  10nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023088(Boc-Phe-His-Sta-Leu-p-methoxybenzylamide | CHEMBL5...)
Affinity DataKi:  12nMAssay Description:Inhibition of human plasma renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084688(2-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataKi:  14nMAssay Description:Binding affinity against aspartic protease renin.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025948(5-Cyclohexyl-3-hydroxy-4-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataKi:  14nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50065425(CHEMBL3401347)
Affinity DataKi:  15nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022519(CHEMBL3349393 | Ibu-His-Pro-Phe-His-Sta-Leu-PheNH2)
Affinity DataKi:  16nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023091(CHEMBL269752 | Iva-His-Pro-Phe-His-Sta-Leu-Phe-NH2)
Affinity DataKi:  17nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)
Affinity DataKi:  18nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405192(CHEMBL2028990)
Affinity DataKi:  18nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405191(CHEMBL269752)
Affinity DataKi:  18nMAssay Description:Inhibition of human kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Displayed 1 to 50 (of 4627 total ) | Next | Last >>
Jump to: