BDBM50371391 SENICAPOC
SMILES NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1
InChI Key InChIKey=SCTZUZTYRMOMKT-UHFFFAOYSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50371391
TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Kca 3.1 (unknown origin)More data for this Ligand-Target Pair
TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of voltage-gated K channel 7.1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of voltage-gated Na channel 1.7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of voltage-gated Na channel 1.6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of voltage-gated Na channel 1.4 (unknown origin)More data for this Ligand-Target Pair
TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of gardos channel (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of voltage-gated Na channel 1.2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of voltage-gated Na channel 1.1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of IK (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of voltage-gated K channel 1.5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of voltage-gated Na channel 1.3 (unknown origin)More data for this Ligand-Target Pair