BDBM10207 5-[(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}-5-phenylpentyl)carbamoyl]-2-hydroxybenzoic acid::amide analog 29

SMILES OC(=O)C[C@H](NC(=O)C(CCCCNC(=O)c1ccc(O)c(c1)C(O)=O)c1ccccc1)C=O

InChI Key InChIKey=JSVOUHNVRPMUNH-ZENAZSQFSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10207   

TargetCaspase-3(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM10207(5-[(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}...)
Affinity DataKi:  400nM ΔG°:  -8.72kcal/moleT: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed