BDBM10260 4-fluoro-N-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)benzamide::Isoquinoline-1,3,4-trione 6g::N-(1,2,3,4-Tetrahydro-1,3,4-trioxoisoquinolin-5-yl)-4-fluorobenzamide

SMILES Fc1ccc(cc1)C(=O)Nc1cccc2C(=O)NC(=O)C(=O)c12

InChI Key InChIKey=LSDAZQSCMLSVKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10260   

TargetCaspase-3(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10260(4-fluoro-N-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50:  99nMpH: 7.5 T: 35°CAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed