BDBM103834 SPI-09::US11041859, Code SPI-09::US9791447, Compound SPI-09

SMILES Nc1ccc2cc(cc(c2c1\N=N\c1ccc(cc1)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O

InChI Key InChIKey=NPWGMYKQRGYORG-VHEBQXMUSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 103834   

TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50: >6.00E+7nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50:  2.34E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50: >6.00E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50:  2.70E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50: >6.00E+4nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50:  6.80E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 7(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50:  1.90E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50: >6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 2/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50:  2.36E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmall ubiquitin-related modifier 1/2(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50: >6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease/Small ubiquitin-related modifier 2(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50:  2.66E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50: >6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50:  6.80E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 7(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM103834(SPI-09 | US11041859, Code SPI-09 | US9791447, Comp...)
Affinity DataIC50:  1.90E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
In DepthDetails US Patent