BDBM29516 Pyranonaphthoquinone (PNQ) lactone, 11f

SMILES O=C1C[C@H]2O[C@@H](c3ccsc3)C3=C([C@H]2O1)C(=O)c1ccccc1C3=O

InChI Key InChIKey=RKONLXIJXZSIBR-HQOQDVMHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29516   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM29516(Pyranonaphthoquinone (PNQ) lactone, 11f)
Affinity DataIC50:  122nMpH: 7.4 T: 2°CAssay Description:AKT1 was assayed using constitutively active Myr-AKT1 in low-binding 96-well plates. The kinase reactions were initiated by the addition of assay mix...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed