BDBM50009057 (R)Methyl-(1-methyl-2-phenyl-ethyl)-amine::METHAMPHETAMINE::METHAMPHETAMINE (+)::METHAMPHETAMINE (-)::Methyl-(1-methyl-2-phenyl-ethyl)-amine::Methyl-(1-methyl-2-phenyl-ethyl)-amine(methamphetamine)

SMILES CNC(C)Cc1ccccc1

InChI Key InChIKey=MYWUZJCMWCOHBA-UHFFFAOYSA-N

Data  22 KI  2 IC50

PDB links: 6 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50009057   

TargetSodium-dependent noradrenaline transporter(Human)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  12.3nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  24.5nMMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetNorepinephrine transporter(Rat)
Nih

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  48nMMore data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetSodium-dependent dopamine transporter(Rat)
Nih

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  114nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
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TargetNorepinephrine transporter(Rat)
Nih

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  234nMMore data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
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TargetSodium-dependent dopamine transporter(Rat)
Nih

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  353nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
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TargetAlpha-1A adrenergic receptor(Rat)
TBA

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  600nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI
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TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  736nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI
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TargetSodium-dependent serotonin transporter(Rat)
Nih

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  2.14E+3nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI
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TargetSodium-dependent dopamine transporter(Rat)
Nih

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  4.84E+3nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
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TargetSynaptic vesicular amine transporter(Human)
Organix

Curated by ChEMBL

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  6.40E+3nMAssay Description:Displacement of [3H]reserpine from human VMAT2 expressed in HEK293 cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetAlpha-1A adrenergic receptor(Rat)
TBA

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  6.70E+3nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI
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Target5-hydroxytryptamine receptor 2A(Rat)
Sri International

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI
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Target5-hydroxytryptamine receptor 3A(Mouse)
Sri International

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI
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Target5-hydroxytryptamine receptor 2C(Rat)
Sri International

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI
Copy reaction URL

Target5-hydroxytryptamine receptor 1A(Human)
Sri International

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI
Copy reaction URL

TargetSodium-dependent serotonin transporter(Rat)
Nih

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI
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TargetD(2) dopamine receptor(Human)
Sri International

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI
Copy reaction URL

TargetD(1A) dopamine receptor(Human)
Sri International

Curated by PDSP K_i Database

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI
Copy reaction URL

TargetSynaptic vesicular amine transporter(Human)
Organix

Curated by ChEMBL

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  2.45E+4nMAssay Description:Displacement of [3H](+)-syn-Ethyl 1-(2-(2,4-Dioxo-1,2-dihydroquinazolin-3(4H)-yl)ethyl)-4-(4-fluorophenyl)piperidine-3-carboxylate from human VMAT2 e...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

Target5-hydroxytryptamine receptor 2A(Human)
Organix

Curated by ChEMBL

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  1.01E+5nMAssay Description:Displacement of [125I]DOI from human 5HT2A receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetSynaptic vesicular amine transporter(Human)
Organix

Curated by ChEMBL

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataKi:  3.46E+5nMAssay Description:Displacement of [3H]DHTB from human VMAT2 expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetSynaptic vesicular amine transporter(Mouse)
Organix

Curated by ChEMBL

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetSynaptic vesicular amine transporter(Human)
Organix

Curated by ChEMBL

LigandBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)Copy SMILESCopy InChI

Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL