BDBM50018919 CHEMBL254578

SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc(cs1)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=KFRKRECSIYXARE-HMAPJEAMSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50018919   

TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50018919(CHEMBL254578)
Affinity DataKd:  8.74E+6nMAssay Description:Binding affinity to human full length recombinant GST-tagged eIF4E expressed in Escherichia coli BL21(DE3) by intrinsic tryptophan fluorescence quenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50018919(CHEMBL254578)
Affinity DataIC50:  4.35E+4nMAssay Description:Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed