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Found 2 Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E' and Ligand = 'BDBM50018919'
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50018919(CHEMBL254578)
Affinity DataIC50:  4.35E+4nMAssay Description:Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50018919(CHEMBL254578)
Affinity DataKd:  8.74E+6nMAssay Description:Binding affinity to human full length recombinant GST-tagged eIF4E expressed in Escherichia coli BL21(DE3) by intrinsic tryptophan fluorescence quenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed