BDBM8366 CHEMBL1809169::US8822448, 147::US9771375, Example 147
SMILES CSc1nn(-c2cccc(C)c2)c2cc(ccc12)C1=CCNCC1
InChI Key InChIKey=NOQBAUMSUUEQPE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 8366
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Rattus norvegicus (Rat))
Astellas Pharma
US Patent
Astellas Pharma
US Patent
Affinity DataIC50: 30nMpH: 8.0Assay Description:The PDE9-inhibiting activity was measured by the following method. That is, to a buffer solution containing tris(hydroxymethyl)aminomethane-hydrochlo...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of KHK-mediated conversion of D-fructose to fructose-1-phosphate after 60 mins by high throughput mass spectrometry analysisMore data for this Ligand-Target Pair