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Found 2 Enz. Inhib. hit(s) with Target = 'Ketohexokinase' and Ligand = 'BDBM8366'
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM8366(CHEMBL1809169 | US8822448, 147 | US9771375, Exampl...)
Affinity DataIC50:  30nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM8366(CHEMBL1809169 | US8822448, 147 | US9771375, Exampl...)
Affinity DataIC50:  34nMAssay Description:Inhibition of KHK-mediated conversion of D-fructose to fructose-1-phosphate after 60 mins by high throughput mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed