Compile Data Set for Download or QSAR
maximum 50k data
Found 95 with Last Name = 'darby' and Initial = 'mv'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.184nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.351nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.542nMAssay Description:Inhibition of human PKCa using histone H1 as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.08nMAssay Description:Inhibition of human SYK using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.39nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.58nMAssay Description:Inhibition of human PKACA using LCGRTGRRNSI as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  1.76nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2.35nMAssay Description:Inhibition of human YES/YES1 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2.68nMAssay Description:Inhibition of human LCK using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetProtein kinase C gamma type(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2.76nMAssay Description:Inhibition of human PKCg using histone H1 as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  3.82nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  5.94nMAssay Description:Inhibition of human AKT1 using KGSGSGRPRTSSFAEG as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  12.4nMAssay Description:Inhibition of human ZAP70 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  18.1nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human FAK/PTK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  20.3nMAssay Description:Inhibition of human CDK4/cyclinD1 using RB-CTF as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  45.8nMAssay Description:Inhibition of human MEK1 using ERK2 as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  76nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  111nMAssay Description:Inhibition of human mTOR/FRAP1 using 4EBP1 as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374126(CHEMBL271794)
Affinity DataIC50:  120nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374150(CHEMBL374651)
Affinity DataIC50:  230nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50182539(CHEMBL202030 | N-methyl-N-(2-(1-ethyl-propyloxy-4-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374131(CHEMBL270917)
Affinity DataIC50:  250nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374162(CHEMBL223162)
Affinity DataIC50:  260nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374156(CHEMBL220774)
Affinity DataIC50:  290nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50182538(CHEMBL202474 | N-(2-(1-ethyl-propyloxy-4-nitrophen...)
Affinity DataIC50:  300nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374153(CHEMBL220793)
Affinity DataIC50:  330nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50205808(CHEMBL223368 | N-[2-(biphenyl-2-ylmethoxy)-4-nitro...)
Affinity DataIC50:  330nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50264841(CHEMBL4076767)
Affinity DataIC50:  356nMAssay Description:Inhibition of recombinant human GST-tagged Mps1/TTK (507 to 1400 residues) using recombinant cetn2 as substrate in presence of [gamma-32P]ATP measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374164(CHEMBL220886)
Affinity DataIC50:  370nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374163(CHEMBL223109)
Affinity DataIC50:  400nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50182541(CHEMBL202473 | N-(2-(cyclopentyloxy)-4-nitrophenyl...)
Affinity DataIC50:  440nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374128(CHEMBL409271)
Affinity DataIC50:  440nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374159(CHEMBL224037)
Affinity DataIC50:  470nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50182545(CHEMBL204183 | N-(2-(cyclohexyloxy)-4-nitrophenyl)...)
Affinity DataIC50:  470nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50205811(CHEMBL376303 | N-(2-(4-nitrobenzyloxy)-4-nitrophen...)
Affinity DataIC50:  490nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374149(CHEMBL436515)
Affinity DataIC50:  520nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374157(CHEMBL373427)
Affinity DataIC50:  580nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  581nMAssay Description:Inhibition of human JNK1 using ATF2 as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374151(CHEMBL373377)
Affinity DataIC50:  650nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  680nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374129(CHEMBL270915)
Affinity DataIC50:  690nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374130(CHEMBL271129)
Affinity DataIC50:  690nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50182542(CHEMBL382482 | N-methyl-N-(2-propyloxy-4-nitrophen...)
Affinity DataIC50:  760nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50053315(CHEMBL3330411)
Affinity DataIC50:  809nMAssay Description:Inhibition of recombinant human GST-tagged Mps1/TTK (507 to 1400 residues) using recombinant cetn2 as substrate in presence of [gamma-32P]ATP measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50205813(CHEMBL222250 | N-(2-(benzyloxy)-4-nitrophenyl)-N-m...)
Affinity DataIC50:  810nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50374152(CHEMBL426541)
Affinity DataIC50:  850nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50182537(CHEMBL437497 | N-(2-(cyclopentyloxy)-4-nitrophenyl...)
Affinity DataIC50:  870nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50264841(CHEMBL4076767)
Affinity DataIC50:  891nMAssay Description:Inhibition of human FAK/PTK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50182532(CHEMBL202469 | N-(2-nonyloxy-4-nitrophenyl)methane...)
Affinity DataIC50:  910nMAssay Description:Inhibition of aromatase in human SKBR3 cells by tritiated water release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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