BDBM50053315 CHEMBL3330411

SMILES COc1cc(ccc1Nc1nc(Nc2ccccc2S(=O)(=O)C(C)C)c2cc[nH]c2n1)N1CCC(O)CC1

InChI Key InChIKey=WRLHYUXLWUWBTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053315   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50053315(CHEMBL3330411)
Affinity DataIC50:  809nMAssay Description:Inhibition of recombinant human GST-tagged Mps1/TTK (507 to 1400 residues) using recombinant cetn2 as substrate in presence of [gamma-32P]ATP measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50053315(CHEMBL3330411)
Affinity DataIC50:  370nMAssay Description:Inhibition of GST-fused full length human TTK compound pre-incubated for 15 mins prior ATP addition by MBP-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed