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Found 210 with Last Name = 'engel' and Initial = 'w'
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029464(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Affinity DataKi:  0.0400nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataKi:  0.110nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50013889((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...)
Affinity DataKi:  0.120nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029464(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Affinity DataKi:  0.470nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataKi:  0.570nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029482(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataKi:  1.20nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029482(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataKi:  1.20nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280292(7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy...)
Affinity DataKi:  1.90nMAssay Description:In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50013889((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...)
Affinity DataKi:  1.90nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280291(7-[3-(4-Ethoxy-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataKi:  3.5nMAssay Description:In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50281875(CHEMBL15648 | {3-[3-(4-Acetyl-2-ethyl-5-hydroxy-ph...)
Affinity DataKi:  5nMAssay Description:Binding affinity against LTB4 receptor in guinea pig membraneMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50226901(CHEMBL280600)
Affinity DataKi:  6nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50281873(CHEMBL15559 | Sodium; 7-[3-(4-acetyl-2-ethyl-5-hyd...)
Affinity DataKi:  10nMAssay Description:Binding affinity against LTB4 receptor in guinea pig membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  14nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  14nMAssay Description:In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50281874(6-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...)
Affinity DataKi:  15nMAssay Description:Binding affinity against LTB4 receptor in guinea pig membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50281876(2-{3-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propo...)
Affinity DataKi:  16nMAssay Description:Inhibition against LTB4 receptor in human neutrophilMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50281877(2-{3-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propo...)
Affinity DataKi:  19nMAssay Description:Binding affinity against LTB4 receptor in guinea pig membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataKi:  22nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021847(5-[2-(4-Methyl-piperazin-1-yl)-acetyl]-5,10-dihydr...)
Affinity DataKi:  23nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280286(4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)h...)
Affinity DataKi:  23nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280290(4-ethyl-2-methoxy-5-[6-methyl-6-(2H-1,2,3,4-tetraa...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280290(4-ethyl-2-methoxy-5-[6-methyl-6-(2H-1,2,3,4-tetraa...)
Affinity DataKi:  25nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  36nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  36nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021850(11-(3-Dimethylamino-propionyl)-5,11-dihydro-benzo[...)
Affinity DataKi:  45nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226900(CHEMBL29330)
Affinity DataKi:  50nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280287(4-ethyl-2-isopropoxy-5-[6-methyl-6-(2H-1,2,3,4-tet...)
Affinity DataKi:  53nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  60nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
Affinity DataKi:  65nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81519(CAS_117690-79-6 | CGS 23356 | CHEMBL15766 | LY 255...)
Affinity DataKi:  78nMAssay Description:Binding affinity against LTB4 receptor in guinea pig membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036749(1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,3,4-tet...)
Affinity DataKi:  78nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280288(4-ethyl-2-isopentyloxy-5-[6-methyl-6-(2H-1,2,3,4-t...)
Affinity DataKi:  83nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280285(2-cyclopentyloxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4...)
Affinity DataKi:  109nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280289(4-ethyl-2-(4-fluorobenzyloxy)-5-[6-methyl-6-(2H-1,...)
Affinity DataKi:  110nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50226898(CHEMBL28973)
Affinity DataKi:  200nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226897(CHEMBL29289)
Affinity DataKi:  200nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226899(CHEMBL31780)
Affinity DataKi:  240nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50:  0.0300nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173482(4-(2-Oxo-4-phenyl-2,3-dihydro-imidazol-1-yl)-piper...)
Affinity DataIC50:  0.0500nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50:  0.0600nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]-CGRP as radioligand after 180 minutes of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50:  0.200nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029464(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataIC50:  1.80nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50:  2.70nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]-CGRP as radioligand after 180 minutes of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280292(7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy...)
Affinity DataIC50:  2.90nMAssay Description:In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataIC50:  3.40nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280291(7-[3-(4-Ethoxy-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataIC50:  4.20nMAssay Description:In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173472(4-(1-Phenyl-ureido)-piperidine-1-carboxylic acid [...)
Affinity DataIC50:  4.70nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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