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Found 125 with Last Name = 'fréchette' and Initial = 's'
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373681(CHEMBL257631)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232653(CHEMBL403467 | N-(2-aminophenyl)-4-((6-methoxybenz...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373683(CHEMBL257835)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232646(CHEMBL254112 | N-(2-aminophenyl)-4-((6-bromobenzo[...)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373686(CHEMBL404332)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373689(CHEMBL271862)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255261(CHEMBL479278 | N-(2-aminophenyl)-4-((4-(6-morpholi...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232650(CHEMBL254519 | N-(2-aminophenyl)-4-((6-(2-morpholi...)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232658(CHEMBL254311 | N-(2-aminophenyl)-4-((6-(2-morpholi...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232656(CHEMBL403465 | N-(2-aminophenyl)-4-((5-phenyl-1H-p...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255101(CHEMBL519604 | N-(2-aminophenyl)-4-((6-(pyridin-3-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255378(CHEMBL480623 | N-(2-aminophenyl)-4-((4-(thiophen-3...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373680(CHEMBL401751)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232648(CHEMBL254309 | N-(2-aminophenyl)-4-((6-methoxy-1H-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232649(CHEMBL254310 | N-(2-aminophenyl)-4-((6-(pyridin-2-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373673(CHEMBL258297)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232660(CHEMBL402599 | N-(2-aminophenyl)-4-((5-phenyl-1,3,...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255425(CHEMBL516236 | N-(2-aminophenyl)-4-((4-(4-(2-morph...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255262(CHEMBL479279 | N-(2-aminophenyl)-4-((4-(6-(4-methy...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232655(4-((1H-benzo[d]imidazol-2-ylthio)methyl)-N-(2-amin...)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255424(CHEMBL481998 | N-(2-aminophenyl)-4-((4-(4-(morphol...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255263(CHEMBL480026 | N-(2-aminophenyl)-4-((4-(6-(methylt...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255917(CHEMBL480923 | N-(2-aminophenyl)-4-((3-(pyridin-3-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373694(CHEMBL271852)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373693(CHEMBL403596)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232647(CHEMBL254111 | N-(2-aminophenyl)-4-((5-chlorobenzo...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373674(CHEMBL269937)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373678(CHEMBL271641)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373684(CHEMBL403285)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373690(CHEMBL271652)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232652(4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-ami...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373691(CHEMBL271100)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232651(CHEMBL253912 | N-(2-aminophenyl)-4-((benzo[d]thiaz...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255102(CHEMBL481211 | N-(2-aminophenyl)-4-((6-(pyridin-3-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255469(CHEMBL480043 | N-(2-aminophenyl)-4-((4-(4-(2-(dime...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50234080(CHEMBL258813 | N-(2-aminophenyl)-4-(3-(4-(pyridin-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255470(CHEMBL480044 | N-(2-aminophenyl)-4-((4-(3-(2-(dime...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255468(CHEMBL515292 | N-(2-aminophenyl)-4-((4-(3-(2-morph...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255379(CHEMBL520084 | N-(2-aminophenyl)-4-((4-(thiazol-2-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255321(CHEMBL479637 | N-(2-aminophenyl)-4-((4-(6-cyanopyr...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255260(4-((4-amino-6-(pyridin-3-yl)pyrimidin-2-ylamino)me...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255099(4-((2,3'-bipyridin-6-ylamino)methyl)-N-(2-aminophe...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255377(CHEMBL480622 | N-(2-aminophenyl)-4-((4-(pyrazin-2-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373675(CHEMBL404054)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232662(CHEMBL253910 | N-(2-aminophenyl)-4-((5-(methylthio...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373688(CHEMBL404518)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50373685(CHEMBL270149)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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