BDBM50232652 4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-aminophenyl)benzamide::CHEMBL403466

SMILES Nc1ccccc1NC(=O)c1ccc(CNc2nc3ccccc3[nH]2)cc1

InChI Key InChIKey=XDBOAFOJZRJJBV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232652   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232652(4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-ami...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232652(4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-ami...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed