Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.870nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of fluorescein isothiocyanate labeled geldanamycin binding to N-terminal domain of full length human recombinant Hsp90alpha expressed in E...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of fluorescien-conjugated coactivator PGC1a binding to ERalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of fluorescien-conjugated coactivator PGC1a binding to GST-tagged human ERRgamma LBD after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Fluor de Lys as substrate incubated with compound for 30 mins by microtiter-plate reading...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Fluor de Lys as substrate incubated with compound for 30 mins by microtiter-plate reading...More data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Binding affinity to ERRgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair