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Found 19 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha' and Ligand = 'BDBM50008059'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  14nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  14nMAssay Description:Inhibition of fluorescein isothiocyanate labeled geldanamycin binding to N-terminal domain of full length human recombinant Hsp90alpha expressed in E...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  27nMAssay Description:Inhibition of HSP90alpha (unknown origin)More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  42nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  42nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  42nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  42nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  44nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  44nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  49nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  49nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  54nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  54nMAssay Description:Displacement of fluorescent labelled-VER00051001 from N-terminal ATP-binding site of human recombinant HSP90A expressed in Escherichia coli measured ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  74nMAssay Description:Displacement of GM-BODIPY from human full length HSP90 alpha expressed in baculovirus-infected Sf9 cells after 16 hrs by fluorescence polarization as...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  100nMAssay Description:Inhibition of HSP90alpha (unknown origin)More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  140nMAssay Description:Displacement of GA-FITC from human recombinant HSP90alpha ATP-binding site by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  272nMAssay Description:Inhibition of recombinant Homo sapiens (human) Hsp90 alpha ATPase activity assessed as inorganic phosphate release by malachite green colorimetric me...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  780nMAssay Description:Inhibition of GA-FITC binding to human recombinant Hsp90alpha incubated for 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataKd:  714nMAssay Description:Binding affinity to N-terminal FLAG-tagged human recombinant HSP90alpha expressed in Escherichia coli BL21(DE3) by microscale thermophoresis assayMore data for this Ligand-Target Pair