TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataKi: 0.470nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataKi: 280nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair