Affinity DataKi: 1.5nMAssay Description:The compound was evaluated for the inhibition of [125I]-Sar-AII binding to Angiotensin II receptor, type 1 from purified rat liver membranes.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:The compound was evaluated for the inhibition of [125I]-Sar-AII binding to Angiotensin II receptor, type 1 from purified rat liver membranes.More data for this Ligand-Target Pair
Affinity DataKi: 12.1nMAssay Description:The compound was evaluated for the inhibition of [125I]-Sar-AII binding to Angiotensin II receptor, type 1 from purified rat liver membranes.More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:The compound was evaluated for the inhibition of [125I]-Sar-AII binding to Angiotensin II receptor, type 1 from purified rat liver membranes.More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Alpha-2 adrenergic receptor activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Alpha-2 adrenergic receptor activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Alpha-2 adrenergic receptor activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 269nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Alpha-2-adrenolytic activity was assessed in vitro from the ability to inhibit norepinephrine binding to guinea pig vas deferensMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of beta-2 adrenergic receptor isolated from rat lung homogenatesMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of beta-2 adrenergic receptor isolated from rat lung homogenatesMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair