BDBM50228237 CHEMBL554455
SMILES Cl.CO\C(O)=C1\C(C(C(=O)OCCN(C)CC2COc3ccccc3O2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O
InChI Key InChIKey=FOFJPGCYRCNMQH-KYYAMWDPSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50228237
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Institut De Pharmacologie (Ua 589 Cnrs)
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair