TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP2C19 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of CYP3A4 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP2C9 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 194nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 447nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 703nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 722nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 2.79E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 5.63E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.28E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
Affinity DataIC50: 7.72E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
Affinity DataIC50: 8.62E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERG potassium channel expressed in HEK293 cell membrane after 1 hrMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair