Compile Data Set for Download or QSAR
maximum 50k data
Found 44 with Last Name = 'nam' and Initial = 'dh'
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CYP2C19 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50167706((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-3-met...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  60nMAssay Description:Inhibition of CYP3A4 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50167706((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-3-met...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50090677(4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfon...)
Affinity DataIC50:  80nMAssay Description:Inhibition of CYP2C9 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343071((S)-2-(3,4-dihydroxybenzylidene)-N-(4-(4-methoxyph...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataIC50:  194nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50236897(3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343074((S)-N-(4-(benzylamino)-3,4-dioxo-1-phenylbutan-2-y...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343070((S)-N-(4-(benzylamino)-3,4-dioxo-1-phenylbutan-2-y...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130509(CHEMBL3634097)
Affinity DataIC50:  447nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343069((S)-3-(2-(3,4-dihydroxybenzylidene)butanamido)-N-(...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343073((S)-2-(3,4-dihydroxybenzylidene)-N-(4-(4-methoxyph...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50265975((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2,...)
Affinity DataIC50:  520nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343068((S)-N-benzyl-3-(2-(3,4-dihydroxybenzylidene)butana...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343075((S)-2-(4-hydroxy-3-methoxybenzylidene)-N-(4-(4-met...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343072((S)-N-(4-(benzylamino)-3,4-dioxo-1-phenylbutan-2-y...)
Affinity DataIC50:  670nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130506(CHEMBL3634110)
Affinity DataIC50:  703nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227403((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-3-met...)
Affinity DataIC50:  710nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50:  722nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227399((S)-N-(4-(4-methoxyphenethylamino)-3,4-dioxo-1-phe...)
Affinity DataIC50:  730nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130507(CHEMBL3634109)
Affinity DataIC50:  1.32E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343076((S)-2-(3,4-dimethoxybenzylidene)-N-(4-(4-methoxyph...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227401((S)-N-(4-(3,4-dimethoxybenzylamino)-3,4-dioxo-1-ph...)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130508(CHEMBL3634099)
Affinity DataIC50:  2.79E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227395((S)-N-(3,4-dioxo-4-(phenethylamino)-1-phenylbutan-...)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227394((S)-N-(4-(4-methoxybenzylamino)-3,4-dioxo-1-phenyl...)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227398((S)-N-(4-(benzylamino)-3,4-dioxo-1-phenylbutan-2-y...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227393((S)-N-(4-(4-fluorobenzylamino)-3,4-dioxo-1-phenylb...)
Affinity DataIC50:  5.63E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343067((S)-N-benzyl-3-(3-(3,4-dihydroxyphenyl)acrylamido)...)
Affinity DataIC50:  6.07E+3nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227392((S)-N-(3,4-dioxo-1-phenyl-4-(2-(pyridin-2-yl)ethyl...)
Affinity DataIC50:  6.28E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227402((S)-N-(3,4-dioxo-1-phenyl-4-(pyridin-2-ylmethylami...)
Affinity DataIC50:  7.72E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227400((S)-3-methyl-N-(4-(methylamino)-3,4-dioxo-1-phenyl...)
Affinity DataIC50:  8.62E+3nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERG potassium channel expressed in HEK293 cell membrane after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227396((S)-N-(4-(ethylamino)-3,4-dioxo-1-phenylbutan-2-yl...)
Affinity DataIC50:  4.02E+4nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50227397((S)-N-(4-(isopropylamino)-3,4-dioxo-1-phenylbutan-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed