Found 26 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 1A2' and Ligand = 'BDBM50236897' 
Affinity DataKi: 3.00E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by 7-ethoxyresorufin O-deethylation (EROD)More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by formation of 6-hydroxywarfarinMore data for this Ligand-Target Pair
Affinity DataKi: 6.80E+4nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 30 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin) using 7-ethoxy-3-cyanocoumarin as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant CYP1A2 using CEC as substrate incubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMT: 2°CAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of human CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as phenacetin O-deethylation after 4 to 40 mins in presence of NADPH by LCMS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of recombinant human CYP1A2 using 3-cyano-7-ethoxycoumarin as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of recombinant human CYP1A2 using 3-cyano-7-ethoxycoumarin as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.29E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
