Affinity DataKi: 7.20E+3nM ΔG°: -29.1kJ/mole IC50: 6.10E+4nMpH: 7.0 T: 2°CAssay Description:The mode of human PLK3 inhibition by LFM-A13 was examined in titration experiments using increasing concentrations of [gamma-32P]ATP and purified N-t...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Purified Plx1 was first incubated with different concentrations of LFM-A13. The substrate, GST-Cdc25 peptide (254-316) and [gamma-32P]ATP were added ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Paradigm Pharmaceuticals
Paradigm Pharmaceuticals
Affinity DataIC50: >5.00E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair