TargetCocaine esterase(Homo sapiens (Human))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Non-competitive inhibition of CES2 in human liver microsomes using fluorescein diacetate as substrate by Lineweaver-Burk plot based Michelis-Menten e...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK2alpha2 (unknown origin) by by exchange curve binding kinetic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at D1 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of SKF38393-induced cAMP accumulation measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Jnk2alpha2More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 12nMAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 17nMAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 19nMAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 25nMAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of dopamine-induced calcium flux preincubated for...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 46nMAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 57nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Antagonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of dopamine-induced calcium flux preincubated for...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Binding affinity to p38alpha (unknown origin) assessed as inhibition of ATF2 phosphorylation preincubated for 4 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 94nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of DNMT (unknown origin) by densitometric analysisMore data for this Ligand-Target Pair
TargetCocaine esterase(Homo sapiens (Human))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair