Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]GR205171 from Mongolian gerbil brain NK1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0646nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0776nMAssay Description:Antagonist activity at recombinant rat OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0813nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.117nMAssay Description:Antagonist activity at recombinant rat OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.117nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]GR205171 from human NK1 receptor in cortex homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Antagonist activity at recombinant human OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.138nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.148nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type A receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.148nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type A receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.148nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type A receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Antagonist activity at recombinant human OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.178nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.209nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.224nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.224nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.224nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at recombinant human OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.251nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.275nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.288nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.295nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.302nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at recombinant human OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.331nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.331nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.355nMAssay Description:Inhibition by displacing [3H]CCK-8S against human Cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.372nMAssay Description:Inhibition by displacing [3H]CCK-8S against human Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Antagonist activity at recombinant human OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.427nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.437nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.537nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.562nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.575nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.603nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.646nMAssay Description:In vitro inhibition of binding of [3H]pCCK-8 against Cholecystokinin type B receptor of guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair