Affinity DataKi: 0.00480nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Inhibitory activity of the compound against Human cathepsin LMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibitory activity of the compound against Human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity for alphav/beta 3 vitronectin receptor in HEK cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity for alphaV-beta5 vitronectin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity for alphaV-beta3 vitronectin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [I125]hU2 from human recombinant urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity for alphaIIb-beta3 vitronectin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibitory activity of the compound against Human cathepsin SMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Inhibitory activity of the compound against Rat cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity for alphaV-beta3 vitronectin receptorMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity for alphaV-beta3 vitronectin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity for alphav/beta 3 vitronectin receptor in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibitory activity of the compound against Human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibitory activity of the compound against Human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibitory activity of the compound against Human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibitory activity of the compound against Human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Binding affinity for alphaV-beta5 vitronectin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibitory activity of the compound against Human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Inhibitory activity of the compound against Human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair