Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50126594'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Affinity DataKi:  32nMAssay Description:Binding affinity for alphaV-beta5 vitronectin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human intergrin alphavbeta3 receptor by solid phase receptor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human intergrin alphavbeta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Affinity DataIC50:  500nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed