Affinity DataIC50: 0.300nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:In vitro inhibition of binding of the compound to GnRH receptor in humanMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of gonadotropin-releasing hormone receptor in rhesus monkeyMore data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.910nMAssay Description:Binding affinity at CB1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Functional antagonism at the human GnRH receptor (PI turnover)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Binding affinity at CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Binding affinity at CB1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Binding affinity at CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Binding affinity at CB1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Binding affinity at CB1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of binding of the compound to GnRH receptor in ratMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Binding affinity at CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair