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Found 22 with Last Name = 'verbruggen' and Initial = 'am'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Imir K.U. Leuven

Curated by ChEMBL
LigandPNGBDBM50349311(CHEMBL1807841)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells after 1 hrs by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Imir K.U. Leuven

Curated by ChEMBL
LigandPNGBDBM50349311(CHEMBL1807841)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]-SR141716A from human CB1 receptor expressed in CHO cells after 1 hrs by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Katholieke Universiteit Leuven

Curated by ChEMBL
LigandPNGBDBM50205239(3-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahyd...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of VZV thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Katholieke Universiteit Leuven

Curated by ChEMBL
LigandPNGBDBM50211001(6-(3-hydroxy-4-iodophenyl)-3-((2R,4S,5R)-4-hydroxy...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of VZV thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205237(9-(4-fluoro-3-hydroxymethylbutyl)guanine | CHEMBL2...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50210804(2-Amino-9-(4-hydroxy-3-hydroxymethyl-butyl)-1,9-di...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205236(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-fluoroethox...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205242(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-methoxyphen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205241(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-fluoropheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205238(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(2-fluoropheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205239(3-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahyd...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205239(3-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahyd...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205238(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(2-fluoropheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50228388(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-methoxyphen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human cytosolic thymidine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50228386(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-hydroxyphen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human cytosolic thymidine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50228389(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-(1-fluoroet...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human cytosolic thymidine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50228387(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-(1-fluorohe...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human cytosolic thymidine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50228390(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-(1-fluorohe...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human cytosolic thymidine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205241(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-fluoropheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205242(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-methoxyphen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205236(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-fluoroethox...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Imir K.U. Leuven

Curated by ChEMBL
LigandPNGBDBM50349311(CHEMBL1807841)
Affinity DataEC50:  17.9nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cells assessed as effect on [35S]-GTPgammaS binding after 1 hrs by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed