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Found 32 with Last Name = 'zadrobilek' and Initial = 'j'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataIC50:  0.770nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataIC50:  8.90nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50:  22nMAssay Description:Inhibition of rat CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218121(CHEMBL390675 | naphthalen-1-yl-(4-pentylaminonapht...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218123(CHEMBL244402 | naphthalen-1-yl-(4-butoxynaphthalen...)
Affinity DataIC50:  48nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218123(CHEMBL244402 | naphthalen-1-yl-(4-butoxynaphthalen...)
Affinity DataIC50:  85nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218120(CHEMBL243334 | naphthalen-1-yl-(4-propoxynaphthale...)
Affinity DataIC50:  90nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50:  98nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218121(CHEMBL390675 | naphthalen-1-yl-(4-pentylaminonapht...)
Affinity DataIC50:  120nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218119((4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanon...)
Affinity DataIC50:  160nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218120(CHEMBL243334 | naphthalen-1-yl-(4-propoxynaphthale...)
Affinity DataIC50:  300nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218119((4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanon...)
Affinity DataIC50:  660nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218122(CHEMBL244607 | naphthalen-1-yl-(4-phenethyloxynaph...)
Affinity DataIC50:  930nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218118(CHEMBL244189 | [4-(2-morpholin-4-ylethoxy)naphthal...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218122(CHEMBL244607 | naphthalen-1-yl-(4-phenethyloxynaph...)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218118(CHEMBL244189 | [4-(2-morpholin-4-ylethoxy)naphthal...)
Affinity DataIC50:  1.10E+4nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50:  8.08E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP2E1 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataEC50:  6.10nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(CHEMBL244403 | naphthalen-1-yl-(4-pentyloxynaphtha...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataEC50:  0.350nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataEC50:  0.470nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair