Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-LY459477 from human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 166nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-Astemizole from human ERG by membrane binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 11.2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 14.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 15.3nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 16.2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 20.7nMAssay Description:Inhibition of mouse p38alpha in anisomycin-stimulated RAW 264.7 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse p38alpha in anisomycin-stimulated RAW 264.7 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Avenida De La Industria
Avenida De La Industria
Affinity DataIC50: 26nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
Affinity DataIC50: 26.1nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 26.2nMAssay Description:Inhibition of mouse p38alpha in anisomycin-stimulated RAW 264.7 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 27.5nMAssay Description:Inhibition of mouse p38alpha in anisomycin-stimulated RAW 264.7 cells by ELISAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Avenida De La Industria
Avenida De La Industria
Affinity DataIC50: 29nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair