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Found 65 with Last Name = 'van de langemheen' and Initial = 'h'
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Glasgow

LigandPNGBDBM218837(TBMB-PK15 (10))
Affinity DataKi:  1.30nMpH: 7.4Assay Description:The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Glasgow

LigandPNGBDBM218839(TBMT-FX618 (16) | TBMT-PK15 (12))
Affinity DataKi:  20nMpH: 7.4Assay Description:The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Glasgow

LigandPNGBDBM218840(TATA-FXII618 (14))
Affinity DataKi:  25nMpH: 7.4Assay Description:The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Glasgow

LigandPNGBDBM218838(TATB-FXII618 (15) | TATB-PK15 (11))
Affinity DataKi:  340nMpH: 7.4Assay Description:The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Glasgow

LigandPNGBDBM218838(TATB-FXII618 (15) | TATB-PK15 (11))
Affinity DataKi:  540nMpH: 7.4Assay Description:The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Glasgow

LigandPNGBDBM218839(TBMT-FX618 (16) | TBMT-PK15 (12))
Affinity DataKi:  1.22E+3nMpH: 7.4Assay Description:The inhibition of plasma kallikrein and coagulation factor FXII was assessed by incubating the proteases with bicyclic peptide (twofold dilutions) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50426994(CHEMBL2326533)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50426994(CHEMBL2326533)
Affinity DataIC50:  28nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50229129(4-Methyl-piperazine-1-carboxylic acid [(S)-1-((E)-...)
Affinity DataIC50:  81nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546078(CHEMBL4750628)
Affinity DataIC50:  106nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274010(CHEMBL4126411)
Affinity DataIC50:  119nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546076(CHEMBL4744708)
Affinity DataIC50:  124nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546077(CHEMBL4742162)
Affinity DataIC50:  129nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274036(CHEMBL4128478)
Affinity DataIC50:  130nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274036(CHEMBL4128478)
Affinity DataIC50:  130nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50273999(CHEMBL4129702)
Affinity DataIC50:  140nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546071(CHEMBL4762654)
Affinity DataIC50:  148nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274011(CHEMBL4125911)
Affinity DataIC50:  150nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546075(CHEMBL4755488)
Affinity DataIC50:  162nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546073(CHEMBL4740177)
Affinity DataIC50:  168nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546074(CHEMBL4799021)
Affinity DataIC50:  168nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546070(CHEMBL4764681)
Affinity DataIC50:  182nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546072(CHEMBL4794953)
Affinity DataIC50:  186nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50546069(CHEMBL4758732)
Affinity DataIC50:  190nMAssay Description:Inhibition of papaya papain assessed as reduction in p-nitoaniline release using Nalpha-benzoyl-L-arginine 4-nitroanilide hydrochloride as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274033(CHEMBL4128898)
Affinity DataIC50:  200nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274026(CHEMBL4129220)
Affinity DataIC50:  200nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274035(CHEMBL4129042)
Affinity DataIC50:  210nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274034(CHEMBL4128074)
Affinity DataIC50:  210nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274033(CHEMBL4128898)
Affinity DataIC50:  220nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274034(CHEMBL4128074)
Affinity DataIC50:  250nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274041(CHEMBL4127967)
Affinity DataIC50:  300nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274008(CHEMBL4126693)
Affinity DataIC50:  350nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50273999(CHEMBL4129702)
Affinity DataIC50:  360nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274010(CHEMBL4126411)
Affinity DataIC50:  395nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274011(CHEMBL4125911)
Affinity DataIC50:  400nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274033(CHEMBL4128898)
Affinity DataIC50:  450nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274041(CHEMBL4127967)
Affinity DataIC50:  470nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274009(CHEMBL4130258)
Affinity DataIC50:  700nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50273998(CHEMBL4129319)
Affinity DataIC50:  700nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274033(CHEMBL4128898)
Affinity DataIC50:  950nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274043(CHEMBL4127928)
Affinity DataIC50:  980nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274026(CHEMBL4129220)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274046(CHEMBL4130108)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50426994(CHEMBL2326533)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274035(CHEMBL4129042)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50426994(CHEMBL2326533)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274036(CHEMBL4128478)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274011(CHEMBL4125911)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274011(CHEMBL4125911)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274036(CHEMBL4128478)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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