BDBM50274033 CHEMBL4128898

SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(N)cc1)CS(F)(=O)=O

InChI Key InChIKey=NMPLEZOMBFJCJD-FWEHEUNISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274033   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274033(CHEMBL4128898)
Affinity DataIC50:  450nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274033(CHEMBL4128898)
Affinity DataIC50:  950nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274033(CHEMBL4128898)
Affinity DataIC50:  220nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274033(CHEMBL4128898)
Affinity DataIC50:  200nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed