Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 160nM
Assay Description:
In vitro binding affinity tested on human Dopamine receptor D2 using [3H]spiperon as a radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 167nM
Assay Description:
Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
In vitro binding affinity tested on human 5-hydroxytryptamine 1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.50E+4nM
Assay Description:
In vitro binding affinity tested on human Dopamine receptor D2 (long) using [3H]spiperon as a radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.10E+4nM
Assay Description:
In vitro binding affinity tested on human Dopamine receptor D2 (short) using [3H]spiperone as a radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.78E+6nM
Assay Description:
In vitro binding affinity tested on human 5-hydroxytryptamine 1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(RAT)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 14.3nM
Assay Description:
In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Copy BDB DOI
Target
D(4) dopamine receptor
(RAT)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 23.2nM
Assay Description:
In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D4 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12.4nM
Assay Description:
D4 efficacy was measured using recombinant human Dopamine receptor D4 expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(RAT)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 14nM
Assay Description:
Agonist activity at rat D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12nM
Assay Description:
Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50145075
(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12.4nM
Assay Description:
In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI