Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 13 hits in this display   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  160nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 using [3H]spiperon as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  167nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity tested on human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  1.50E+4nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 (long) using [3H]spiperon as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  5.10E+4nMAssay Description:In vitro binding affinity tested on human Dopamine receptor D2 (short) using [3H]spiperone as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataKi:  2.78E+6nMAssay Description:In vitro binding affinity tested on human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  14.3nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  12nMMore data for this Ligand-Target Pair
In DepthDetails
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  23.2nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  12.4nMAssay Description:D4 efficacy was measured using recombinant human Dopamine receptor D4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at rat D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  12.4nMAssay Description:In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed