Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50113049((2R,4R)-2-Hydroxycarbamoyl-1-(4-methoxy-benzenesul...)Copy SMILESCopy InChI

Affinity DataIC50:  19nMAssay Description:Inhibitory concentration of the compound against Matrix metalloproteinase-1 was determinedMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50113049((2R,4R)-2-Hydroxycarbamoyl-1-(4-methoxy-benzenesul...)Copy SMILESCopy InChI

Affinity DataIC50:  9.60E+3nMAssay Description:Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI