Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234860(US9353116, 19 | US9353116, Fig. 16, Compound 1)
Affinity DataIC50:  45.5nMAssay Description:In vitro kinase assays using LRRK WT and LRRK G2019S.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234860(US9353116, 19 | US9353116, Fig. 16, Compound 1)
Affinity DataIC50:  213nMAssay Description:In vitro kinase assays using LRRK WT and LRRK G2019S.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533,T338C](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234860(US9353116, 19 | US9353116, Fig. 16, Compound 1)
Affinity DataIC50:  1.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234860(US9353116, 19 | US9353116, Fig. 16, Compound 1)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent