BDBM234860 US9353116, 19::US9353116, Fig. 16, Compound 1
SMILES COc1cc2ncnc(Nc3cccc(NS(=O)(=O)C=C)c3)c2cc1OC
InChI Key InChIKey=XWEWXOXVGICYJP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 234860
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 213nMAssay Description:In vitro kinase assays using LRRK WT and LRRK G2019S.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533,T338C](Gallus gallus (Chicken))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 1.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 45.5nMAssay Description:In vitro kinase assays using LRRK WT and LRRK G2019S.More data for this Ligand-Target Pair