Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Sentrin-specific protease 6
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.07E+3nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Caspase-9
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.75E+3nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Sentrin-specific protease 8
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.57E+3nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Dual specificity protein phosphatase 6
(Rattus norvegicus)
University of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.31E+3nM
Assay Description:
The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Apoptotic protease-activating factor 1
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.26E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Dual specificity protein phosphatase 6
(Rattus norvegicus)
University of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.42E+4nM
Assay Description:
The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Dual specificity protein phosphatase 1
(Homo sapiens (Human))
University of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.53E+4nM
pH: 7.0 T: 2°C
Assay Description:
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Diphosphomevalonate decarboxylase
(Streptococcus pneumoniae D39)
Srmlsc
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.69E+4nM
Assay Description:
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Caspase-3
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.66E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Dual specificity protein phosphatase 1
(Homo sapiens (Human))
University of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.41E+4nM
Assay Description:
The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Mannose-6-phosphate isomerase
(Homo sapiens (Human))
Sanford-Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.00E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Dual specificity protein phosphatase 1
(Homo sapiens (Human))
University of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Dual specificity protein phosphatase 1
(Homo sapiens (Human))
University of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Mannose-6-phosphate isomerase
(Homo sapiens (Human))
Sanford-Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
pH: 7.4 T: 2°C
Assay Description:
The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Dual specificity protein phosphatase 6
(Rattus norvegicus)
University of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Apoptotic protease-activating factor 1
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Dual specificity protein phosphatase 6
(Rattus norvegicus)
University of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+5nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Tyrosyl-DNA phosphodiesterase 2
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.28E+5nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Bcl-2-related protein A1
(Homo sapiens (Human))
Nmmlsc
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.61E+4nM
pH: 7.4 T: 2°C
Assay Description:
The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM30725
(MLS000079925 | N-[3-cyano-1-(4-methoxyphenyl)-2-py...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.14E+4nM
pH: 7.4 T: 2°C
Assay Description:
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI