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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloproteinase-2 MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against endothelin converting enzyme (ECE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed