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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Adenosine receptor A2b
(Homo sapiens (Human))
Universidade Do Porto
Curated by
ChEMBL
Ligand
BDBM50333651
(4-oxo-N-phenyl-4H-chromene-3-carboxamide | CHEMBL1...)
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Affinity Data
Ki: 8.51E+3nM
Assay Description:
Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
University Of Porto
Curated by
ChEMBL
Ligand
BDBM50333651
(4-oxo-N-phenyl-4H-chromene-3-carboxamide | CHEMBL1...)
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Affinity Data
IC50: 71nM
Assay Description:
Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
University Of Porto
Curated by
ChEMBL
Ligand
BDBM50333651
(4-oxo-N-phenyl-4H-chromene-3-carboxamide | CHEMBL1...)
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Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
Inhibition of human recombinant MAOB expressed in baculovirus-infected BTI insect cells after 15 mins by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
University Of Porto
Curated by
ChEMBL
Ligand
BDBM50333651
(4-oxo-N-phenyl-4H-chromene-3-carboxamide | CHEMBL1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
Inhibition of human MAO-B assessed as inhibition of p-tyramine oxidation to p-hydroxyphenyl-acetaldehyde after 15 mins by fluorimetric method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI