Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandBDBM31930(carbohydrazide derivative, 3m)Copy SMILESCopy InChI

Affinity DataIC50:  1.42E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoDrugBankPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL

LigandBDBM31930(carbohydrazide derivative, 3m)Copy SMILESCopy InChI

Affinity DataEC50:  1.60E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoDrugBankPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI